Opioids aren't sleep aids... (2024)

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The word morphine is derived from Morpheus, the Greek god of dreams. If you’ve ever been on a painkiller like morphine, you know that a side effect is drowsiness. However, using morphine—or any opioid—to help you sleep is extremely dangerous. And yet many people are doing just that. In fact, a recent study revealed that doctors have noticed patients are using opioids to help them fall asleep when acute pain is keeping them up, or because of simple insomnia. And many patients don’t realize the harm in that habit.

Opioids and sleep aids are two entirely different types of drugs: Opioids are powerful narcotics whereas sleep aids are soporific and hypnotic, aka sleep-inducing. These two kinds of medication are intended for two very different purposes—and you shouldn’t use one in place of the other.

What counts as opioid or sleep aids?

The class of drugs called “opioids” include prescription painkillers such as oxycodone (OxyContin), hydrocodone (Vicodin and Percocet), and codeine, as well as synthetic opioids such as fentanyl and the illegal drug heroin.

Commonly prescribed sleep aids include zolpidem tartrate (Ambien, Ambien CR), flurazepam hydrochloride (Dalmane), triazolam (Halcion), eszopiclone (Lunesta), and estazolam (Prosom).

Why shouldn’t you use opioids as sleep aids?

“Certainly opioids can make you drowsy, but they should never be used as a sleep aid,” says Wilson Compton, MD, deputy director of the National Institute on Drug Abuse in Rockville, Maryland. “They’re not safe, with their potential for addiction and other complications. They’re only for acute pain, and in some cases, chronic pain.”

While opioids may help you fall asleep, they do not help you get better sleep. “Opioids lower the rate of REM and slow-wave sleep necessary for restful, recharging sleep,” explains Yili Huang, DO, director of the Pain Management Center at Northwell Phelps Hospital in Sleepy Hollow, New York.

Opioids and sleep apnea

Additionally, between 7% to 20% of Americans have undiagnosed sleep apnea, Dr. Huang says, and for those people, opioids could interfere with their ability to breathe while asleep, potentially endangering their lives. A small study found that the higher the opioid dose, the higher the number of sleep apnea episodes. Other research showed that oxygen saturation dipped sharply just 15 minutes after taking an opioid in the middle of the night. Meaning, opioids may depress respiration for people with sleep apnea, increasing risk of death.

Dr. Compton adds that if you’re already taking opioids for pain management and increase your dosage at night to help you sleep, you’re risking a serious chance of an overdose.

What if I’m in pain and I can’t sleep?

Acute pain can have many sources, whether it’s from a surgical operation, cancer treatment, a chronic pain-inducing medical condition, or a physical accident. But what should you do if you’re in terrible pain and can’t sleep because of it?

“Talk to your doctor about safe alternatives,” Dr. Huang recommends firstly. “Treat what’s causing the pain with more directed treatment at its source. If it’s temporary insomnia along with nerve pain, certain nerve pain medications can treat the pain and also induce sleep, and they can be helpful. Gabapentin [a prescription drug often used relieve nerve pain as a result of shingles in adults] is one such medication. But there’s no magic bullet—all medications have side effects.”

And what you don’t want to do, Dr. Huang says, is to continue taking your opioids while taking sleep aids or sedatives such as Ambien, Xanax, or Valium. This combo increases the chance of respiratory depression (hypoventilation). Combining opioids with any other sedative—including alcohol—creates serious risk for overdose, and even death, Dr. Compton remarked.

If you’re having trouble sleeping, you can also turn to solutions that don’t involve prescription medication, says Dr. Laura Fanucchi, associate professor of medicine at the University of Kentucky and an opioid addiction specialist. These alternatives include behavior changes like:

  • Getting regular exercise
  • Optimizing sleep hygiene by not eating late
  • Avoiding stimulants like caffeine and nicotine
  • Restricting electronic screens (such as cell phones, tablets, TVs, and PC monitors) before bedtime

Why if I’m already dependent on opioids to sleep?

If you’ve already developed a habit of taking opioids for reasons other than prescribed, you should see your doctor right away, Dr. Fanucchi recommends, rather than attempting to go cold turkey. “Daily use of opioids can cause physical dependence and then withdrawal if opioids are stopped suddenly,” she says.

Dr. Huang agrees, “Work with your doctor and come up with a good regimen to strengthen your body. If you’re using these just for sleep, you may be misusing these medications and should consider seeing an addiction doctor. You should see a pain management specialist to treat the source of the pain, because these pills may just be masking the underlying problem.”

Opioids aren't sleep aids... (2024)

FAQs

Why can't I sleep after taking pain meds? ›

Some pain medication may carry side effects that interfere with sleep. Opioid-based pain medication like Codeine, Morphine, Tramadol and Oxycodone can increase or cause breathing problems during sleep and antidepressant drugs may increase leg restlessness. In turn this can result in the use of sleeping tablets.

What happens if you take pain killer and sleeping medicine together? ›

Stanford researchers have determined that taking strong prescription painkillers together with sleeping pills is associated with greater risk of overdose. Ninety-one Americans die every day from an opioid overdose -- a number that has quadrupled since 1999, according to the Center for Disease Control and Prevention.

Does painkiller induce sleep? ›

Codeine (in Panadeine, Panadeine Forte or Nurofen Plus), tramadol, tapentadol, morphine or oxycodone will make us sleepy, but they're not recommended to treat insomnia. These powerful medicines are best reserved for judicious use in pain relief, given the severe hazards of dependence and overdose.

What is the strongest herb for sleep? ›

Results from multiple studies indicate that valerian — a tall, flowering grassland plant — may reduce the amount of time it takes to fall asleep and help you sleep better.

Do opioids make it harder to sleep? ›

Regular, chronic use of opioids is known to interfere with sleep via several mechanisms. It can lead to changes in sleep architecture including a reduction in sleep efficiency as well as slow wave sleep. There also may be a reduction in rapid eye movement (REM) sleep.

Why do pain pills keep me awake? ›

Although pain medication will temporarily relieve pain and help you fall asleep, narcotic pain meds can also cause insomnia. Prescribed painkillers can affect the body's REM cycle and irregular sleep patterns. Changing doses of medication can also affect your ability to sleep.

Which painkiller is best for sleeping? ›

Acetaminophen helps to reduce fever and/or mild to moderate pain (such as headache, backache, aches/pains due to muscle strain, cold, or flu). The antihistamine in this product may cause drowsiness, so it can also be used as a nighttime sleep aid.

What is the natural drug that helps you sleep? ›

Use melatonin supplements .

“Melatonin is a hormone that is naturally released in the brain four hours before we feel a sense of sleepiness,” Gamaldo says. It's triggered by the body's response to reduced light exposure, which should naturally happen at night.

Can you take over the counter sleep aid with hydrocodone? ›

Don't take sleeping pills with opioids.

They include prescription medicines, such as oxycodone, hydrocodone, morphine, methadone and the synthetic opioid fentanyl. This class also includes illegal drugs, such as heroin. Combining an opioid with sleeping pills can be dangerous.

What is the safest sleep aid to take every night? ›

Melatonin: Melatonin is considered one of the safest over-the-counter sleep aids, with few side effects. A prescription drug called ramelteon is designed to mimic the effects of melatonin. Like melatonin, it is not considered habit-forming and it does not affect balance.

What is the new non-addictive sleeping pill? ›

QUVIVIQ® (daridorexant)

What do Native Americans use for sleep remedies? ›

Valeriana sitchensis, a species widely distributed throughout western North America, is one of over 15 valerian species native to the United States. It is smoked as a ritual tobacco by a number of North American Indian tribes. Valerian remains among the top ten most popular herbal remedies sold in the United States.

What to do if you can't sleep because of medication? ›

Taking your medication earlier in the day might reduce sleep side effects. Your doctor may suggest a natural sleep aid like melatonin or a prescription sleeping pill. Ask whether your condition can be treated without medication. For example, therapy may help you just as much as an antidepressant.

Do painkillers interrupt sleep? ›

Unfortunately, some of the medications prescribed for pain, such as codeine and morphine, can cause insomnia. These opioid pain medications can cause apnea, brief pauses in breathing, during sleep.

What to do if you can't sleep because of pain? ›

If you find yourself ruminating or if you are in too much pain to sleep, don't stay in bed. Get up, go to another room, and distract yourself with something else for a while. When you feel sleepy, try going to bed again. Talk to your doctor or mental health professional for more help with sleep and pain management.

Why shouldn't you lay down after taking pain medication? ›

Stand or sit when swallowing medicines. Take several swallows of liquid before taking the medicine, and swallow the medicine with a full 8 oz. glass of liquid. Do not lie down immediately after taking medicine, to make sure the pills have gone through the esophagus into the stomach.

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